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KMID : 0614620160670040216
Korean Journal of Gastroenterology
2016 Volume.67 No. 4 p.216 ~ p.219
A Case of Severe Peripheral Polyneuropathy Occurring after Entecavir Treatment in a Hepatitis B Patient
Song Ji-Hyun

Kim Si-Yeon
Shin Jae-Kyoung
Hong So-Dam
Rim Kyu-Sung
Park Ha-Na
Lee Joo-Ho
Lee Yun-Bin
Oh Seung-Hun
Hwang Seong-Gyu
Abstract
Entecavir (Baraclude¨Þ) is an oral antiviral drug used for the treatment of HBV. Entecavir is a reverse transcriptase inhibitor which prevents the HBV from multiplying. Most common adverse reactions caused by entecavir are headache, fatigue, dizziness, and nausea. Until now, there has been no report of peripheral neuropathy as a side effect associated with entecavir treatment. Herein, we report a case of peripheral neuropathy which probably occurred after treatment with entecavir in a hepatitis B patient. The possibility of the occurrence of this side effect should be carefully taken into consideration when a patient takes a high dose of entecavir for a long period of time or has risk factors for neuropathy at the time of initiating entecavir therapy.
KEYWORD
Entecavir, Polyneuropathies, Hepatitis B
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